Are fitbands the future of genetic research?

Data from personal bio-monitoring devices such as fitbands and smart watches, when combined with genetic information, could be a powerful tool in medical research. But what will all this tell us about ourselves. Science writer Kat Arney finds out.

Thanks to advances in DNA sequencing technology, researchers around the world are now faced with a deluge of genetic data gathered from hundreds of thousands of people.

Despite the headlines claiming to have found "genes for" everything from alcoholism to Alzheimer's disease, we actually know relatively little about how the strings of DNA letters that make up our genome influence our bodies and brains, either in sickness or in health.

The challenge now is to marry up all this genetic data with living, breathing reality, figuring out how variations in each person's genome contribute to their health and wellbeing.

At Stanford University in California, Stephen Montgomery and his team are using the latest DNA-reading technology and sophisticated algorithms to work out how tiny variations across our genomes affect when and where genes are turned on.

These aren't big changes, but subtle differences that dial gene activity up or down just a little bit. And those small changes can make all the difference.

As Stephen tells me, seemingly minor variations in our DNA code can have a big impact on our health and well-being. "For instance, someone might be able to fight off an infection slightly better than someone else. Or someone responds to a drug better than someone else," he explains.

"We want to be able to describe those benefits so that they might be able to help us understand what makes each of us unique, but also to understand how we might use that to tailor any particular treatments for any individual."

To do this properly, we need more data - not just about each person's individual genetic makeup, but information about how their body is changing over time and responding to their environment, diet and lifestyle.

The biggest challenge here is how to gather this information in an effective and relatively hassle-free way. Nobody wants to be dragged into the doctor's surgery every month, week or day for a check-up, even if it might help protect their health in the long term.

Luckily, technology seems to have provided us with a solution. The recent rise of the "measured self" movement, dominated mainly by wearers of personal bio-monitoring devices such as fitbands and smart watches, could provide the vital statistics that this new generation of geneticists need.

At the moment, these devices are relatively simple. The cheapest are basic movement trackers, while more expensive models monitor heart rate. But developers are busy working on wearable technology to track blood pressure, blood sugar levels and all sorts of other parameters.

They may be giving geeks everywhere a whole new set of graphs to play with, but combined with genetic information, the data from these wristbands could prove life-saving.

"We've never had this kind of data," Dr Montgomery tells me. "We don't know what the genetic effects are on this data over time. Even when you go to the doctor you're just getting a readout of this one snapshot in time."

And for people whose blood pressure rises at the mere mention of medical matters, that single reading might not be a reflection of their day-to-day state.

There's also an added dimension of complexity: time. Just as you don't have the same photo in your passport when you' re 40, 60 or 80 as you did when you were 20, we shouldn't think of analysing someone's genome as a one-off snapshot.

According to Dr Montgomery: "We know that there are a lot of changes as people age and it' s different for men and women, from childhood to puberty to menopause. So as well as being able to survey your blood pressure and so on over time, you may get a very detailed understanding of the behaviour of your genes at any point in time and that will inform you to a much higher degree about your overall health and well-being."